Mycobacterial disease in renal allograft recipients

Copyright: © 2013 Ardalan M. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Solid Organ Transplant (SOT) recipients have impaired cellmediated immunity, and are at increased risk of Mycobacterial infection. Mycobacterium tuberculosis infection (TB) has a high mortality rate among this population. The cumulative incidence of post-transplant TB in European and American SOT recipients ranges from 0.35% to 5% while in developing countries, the incidence is as high as 15% in some areas of high TB endemic [1-3]. That is up to 100-fold higher than that observed incidence in the general population in the respective countries [2,3] additionally, renal allograft recipients also coming from dialysis that is a hazardous environment to be infected with TB [4].